The Gran Sasso and Monti della Laga National Park is a natural park located mostly in Abruzzo, Italy. It was established in 1991, it has an area of 2,014 square kilometres, and it is mainly spread out across the province of Teramo, L'Aquila, Pescara, with small areas in the province of Rieti and Ascoli Piceno. The terrain is predominantly mountainous with alpine plains.
It is managed by Ente Parco Nazionale Gran Sasso e Monti della Laga, with headquarters in Assergi, L'Aquila.
The Grand Highway of the Gran Sasso and Monti della Laga National Park runs through the park between the Gran Sasso mountain peak and the chain known as Monti della Laga.