Puyehue National Park is located in the Andes mountain range, in Los Ríos and Los Lagos regions of Chile formerly referred to as the 10th region. The park boast 220,000 acres of natural thermal springs, volcanoes, and evergreen forests, after having been expanded in 1950 and 1981. The park is Chile's most visited national park with 400,000 people enjoying it each year. Puyehue National park forms part of the Reserve of Temperate Rainy Forest Biospheres of the Southern Andes. Chile Route 215 passes through the park, which connects with the Argentine Route 231 via Cardenal Antonio Samoré Pass.