Rodolfo Emilio Giuseppe Pichi-Sermolli was an Italian botanist.
He was born in Florence, son of Giuseppe Pichi-Sermolli and Maria née Del Rosso. He graduated in natural history from the University of Florence in 1935. He married Carla Bernardini on 9 April 1942, and they went on to have two children.
He was assistant at the Institute of Botany in the University of Florence from 1935 to 1958, then became professor of botany at the University of Sassari in Sardinia from 1958 to 1959. From 1959 he was professor at the Institute of Botany in the University of Genoa and director of the Botanical Garden.
He was a specialist on the ecology and phytogeography of tropical Africa, and also worked in plant taxonomy and pteridology.