The Saint Gayane Church is a 7th-century Armenian church in Vagharshapat, the religious center of Armenia. It is located within walking distance from the Etchmiadzin Cathedral of 301. St. Gayane was built by Catholicos Ezra I in the year 630. Its design has remained unchanged despite partial renovations of the dome and some ceilings in 1652.
Gayane was the name of an abbess who was martyred with other nuns by Tiridates III of Armenia in the year 301, and subsequently made a saint of the Armenian Apostolic Church.
In 2000, Saint Gayane Church was listed in the UNESCO World Heritage Sites along with historical churches of Vagharshapat.