Zacatelco is a city and capital of Zacatelco municipality located south of the state of Tlaxcala. According to the population census conducted by the National Institute of Statistics and Geography 2010, the city has a population of 38.466 people, it is the sixth most populous city in the state and is part of the Metropolitan area of Puebla. The city is also head of the third electoral district of Tlaxcala.
The city was founded on December 1, 1529, by Agustín de Castañeda. In 1723 it is very important because it forms Zacatelco republic; this is achieved by joining the towns of San Juan, San Lorenzo, Santo Toribio, Santa Catarina, San Marcos and San Antonio, which depended on Tepeyanco. The most important historical figures of the city were the brothers Arenas, prominent revolutionaries. Domingo Arenas took the first land committee of Mexico in 1915, was one reason for coining the phrase battle: Zacatelco; the heart of south.
Zacatelco is located in the southern part of the valley of Tlaxcala, on the border with the state of Puebla, is at an altitude of 2,210 meters above sea level, making it one of the highest cities in Mexico.