Farmigea, a Journey into the History of a Company

The history of the Italian company Farmigea through the documents and artifacts preserved in its archive

By Museimpresa

Archivio Storico Farmigea

Archivio Storico Farmigea - Exhibition space with woman (Second half of the 1940s)Museimpresa

1946 - The Birth of Farmigea

On April 24, 1946, at 2 Via Carmignani in the historic center of Pisa, a group of entrepreneurs led by Giuseppe Rossini and Antonio Federighi founded "Farmigea". This marked the beginning of an important chapter in Italian pharmaceutical industrial history.

In the very early years of operation, the newly established pharmaceutical company in the pharmaceutical chemistry sector produces and markets generic pharmaceutical products inspired by German and American sources. However, due to the lack of originality in these products and limited marketing investments, the company struggles to achieve a positive financial outcome in its financial statements.

Archivio Storico Farmigea - Historical sample of the Triosex product, Arti Grafiche F.lli Pellegrini, 1960s, From the collection of: Museimpresa
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Archivio Storico Farmigea - Historical sample of the Lipocortex Forte product, Arti Grafiche F.lli Pellegrini, 1960s, From the collection of: Museimpresa
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Archivio Storico Farmigea - Brochure, 1950s, From the collection of: Museimpresa
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Archivio Storico Farmigea - Historical sample of the Poliplacen product, October 1955, From the collection of: Museimpresa
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Archivio Storico Farmigea - Antonio FederighiMuseimpresa

1949 - The era of the Federighi family begins

The less-than-promising start prompted Rossini and the other partners to sell the company within three years of its founding. In February 1949, Antonio Federighi, seeking to invest in the pharmaceutical sector, acquired Farmigea in its entirety.

Archivio Storico Farmigea - Metifen eye drops advertising brochure (1950s)Museimpresa

The 1950s and Specialization in Ophthalmology

In the 1950s, Leopoldo Federighi, the son of founder Antonio Federighi, decided to specialize the company in the field of ophthalmology, a choice reinforced by excellent relationships with the academic world.

Archivio Storico Farmigea - Ophthalmic specialty price list (1957) by Mario MelandriMuseimpresa

There are many price lists and brochures dedicated to eye drops stored in the company's archive. Some of these feature very unique and modern graphics like this one, whose illustration, crafted by the hand of Mario Melandri.

Archivio Storico Farmigea - Eye drops bottle (1950s)Museimpresa

A New Shape for Eye Drops

Interesting fact: The eye drops the company made back then were pioneering, coming in a squeezable plastic container with a distinctive curved spout for enhanced convenience.


Before, eye drops used to be in glass bottles with an inconvenient dropper in the cap.

Archivio Storico Farmigea - Congo minister under the Tower of PisaMuseimpresa

The 1960s and the relationships with Congo

During the 1960s, under the leadership of Leopoldo Federighi, there was a significant push for international expansion. Farmigea, in particular, directed a substantial effort toward Congo, forging numerous and enduring commercial partnerships in the region.

Leopoldo Federighi identified a promising business opportunity during his numerous personal trips to the African country. This prompted him to establish Farmigea's branch in Congo. Subsequently, thanks to Leopoldo's extended stays in various regions of Congo, the opportunity emerged not only to export products but also to initiate local production. Consequently, Farmigea, in collaboration with the Biagini Institute, founded FARBIA with the aim of solidifying their presence in the Congo's market.

Archivio Storico Farmigea - Congo minister in the laboratoryMuseimpresa

The ministerial visits from Congo

The significant decade-long partnership between Farmigea and the Congo is evident through two Congolese ministerial delegations' visits to Pisa. They toured the historical facilities, gaining firsthand knowledge of the production site and signing important commercial agreements.

In Farmigea's archives, we store some of Leopoldo Federighi's correspondence from Congo. He wrote regularly to both the company and his family. What's intriguing about this material, besides its ability to reconstruct the company's dynamics and Leopoldo's personal experiences, is its indirect portrayal of the political evolution in the African country. Notably, postage stamps reveal the stages of the deep crisis that swept through the nation during those years.

Archivio Storico Farmigea - Letter from the Etat du Katnaga, From the collection of: Museimpresa
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Archivio Storico Farmigea - Letter from FarBia (Farmigea Biagini), 1966, From the collection of: Museimpresa
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Archivio Storico Farmigea - Katanga stamp set with postmark cancellation, From the collection of: Museimpresa
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Archivio Storico Farmigea - Letter to Misses Employed of Farmigea, From the collection of: Museimpresa
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Archivio Storico Farmigea - Table flag of the Democratic Republic of Congo, 1966/1971, From the collection of: Museimpresa
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Archivio Storico Farmigea - Farmigea's interiorMuseimpresa

The 1966 flood

Just like Florence, Pisa was also hit by the flood on November 4, 1966. The Farmigea headquarters, located just a few hundred meters from the Arno River, were also engulfed by water and mud, resulting in significant damage, as attested by numerous photographs and documents.

Archivio Storico Farmigea - Gynecologic Specialty List (1990s)Museimpresa

The 1970s and the new gynecological product line

In the 1970s, alongside the ophthalmic line, there was an especially innovative gynecological line that remained part of the company's assets until 2008.

In 1971, Farmigea became a joint-stock company, assuming its final name, Farmigea S.p.A. While Leopoldo was overseeing affairs in Congo, his younger brother, Alberto Federighi, took over the company's leadership. With the assistance of Professor Bianchini, they decided to introduce a gynecological product line alongside the ophthalmic line.

Archivio Storico Farmigea - Brochure of the gynecological product Trichomicida (Trichomycide). (1980s) by Litografia TacchiMuseimpresa

The product brochures of those years were characterized either by images inspired by the classical world or, as in this case, by the pathogenic microorganisms that the products aimed to combat.

Archivio Storico Farmigea - Technical drawings of the monodoses attached to the patent (1982)Museimpresa

The 1980s and the reclosable single-dose eye drop

The technology and the patent for the 'Reclosable Single-Dose Preservative-Free Eye Drops' bear the name of Farmigea and were the result of an extraordinary vision that the company had in the early '80s

In the late 1970s, Alberto and Leopoldo Federighi approached Farmigea's Research Department with a visionary request: to develop an initial conceptual project for their groundbreaking idea of creating sterile single-dose containers tailored to preserve preservative-free eye drops. The Research Department crafted initial technical designs with a primary focus on the container's shape, now an iconic feature with its distinctive side flaps. 

Archivio Storico Farmigea - Pictograms for single-dose eye drops (1982)Museimpresa

This innovative design aimed to tackle two crucial challenges: streamlining industrial packaging processes and ensuring patients could effortlessly use the container, all while securely resealing it for optimal product preservation.

Archivio Storico Farmigea - Prototype container for single-dose eye drops (1982)Museimpresa

Fun fact: the first pilot batches were packaged in aluminum cases. This solution, while practical for initial experimental phases, was never marketed and was soon replaced by a more functional alternative: the use of plastic containers.

Archivio Storico Farmigea - Production of drugs in a sterile environment (1987)Museimpresa

The 1990s and the innovative new technologies

The 1990s marked an extremely prosperous period for Farmigea, as it introduced significant and innovative additions to its product portfolio and new production technologies.

Archivio Storico Farmigea - Worker in the new production plant (2001)Museimpresa

The 2000s and the new course

In 2001, through a Family Buyout operation, Mario and Federigo Federighi acquired the majority of the company. They relocated the plant from the historic center of Pisa to an industrial area with a new production facility.

Archivio Storico Farmigea - Anatomical Model of an Eye (First half of 1900s)Museimpresa

A look into the future

Today, Farmigea is entering its fourth generational transition, with a continued focus on maintaining a strong connection between innovation and tradition.

Credits: All media
The story featured may in some cases have been created by an independent third party and may not always represent the views of the institutions, listed below, who have supplied the content.
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