Notre-Dame-des-Sept-Douleurs is an island municipality in the Bas-Saint-Laurent region of Quebec, Canada, part of the Rivière-du-Loup Regional County Municipality. It is located on and contiguous with Île Verte in the Saint Lawrence River, about 20 kilometres north-east of Rivière-du-Loup. The name Île Verte was given in 1621 by Samuel de Champlain written "Isle Verte".
With a population of only 49 persons, Notre-Dame-des-Sept-Douleurs is one of the smallest municipalities in Canada.
The main economic activities are fishing and tourism. Many fish smokehouses are present on the island. The presence of the oldest lighthouse in Quebec, its pastoral character, skeleton museum, many artists and heritage homes also attract tourists.